Repurposing heart drugs to target cancer cells
A discussion of the potential to repurpose cardiac glycosides, currently used to treat cardiac arrythmias and atrial fibrillation, to treat cancer.
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Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer
Researchers have revealed the important role of epigenetic regulation-mediated metabolic reprogramming in lung cancer’s capacity to resist molecular targeted therapy.
Read MoreOvarian cancer cells stop moving when deprived of the protein Ran
Researchers have shown the key role that a protein called Ran plays in the mobility of ovarian cancer cells. They demonstrated these cells cannot migrate from cancerous sites without the help of Ran.
Read MoreLight therapy could replace opioids as main treatment for cancer treatment side effect
A worldwide coalition of researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy.
Read MoreDiscovery of mechanism behind precision cancer drug opens door for more targeted treatment
New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy.
Read MoreScientists discover origin of cell mask that hides stomach cancer
A layer of cells that look like normal stomach lining on top of sites of stomach cancer can make it difficult to spot after removal of a Helicobacter pylori infection.
Read MoreBiliary microbiome altered after neoadjuvant therapy for pancreatic cancer
The biliary microbiome – the collection of bacteria present in the bile ducts – was altered in patients who received neoadjuvant therapy prior to undergoing surgery for pancreatic cancer.
Read MoreNew probe could help surgeons more accurately remove tumours
A study led by researchers at RCSI’s Department of Chemistry has the potential to help surgeons more accurately remove tumours and detect cancer in lymph nodes during surgery.
Read MoreResearchers identify effective drug combination against uveal melanoma
Researchers have identified a new drug combination that is effective against metastatic uveal melanoma cells in preclinical studies.
Read MoreNatural antioxidant helps improve immune-based therapies by modulating T-cells
Researchers have discovered a way to improve immune-based treatments, such as adoptive T-cell therapy (ACT) and haematopoietic stem cell transplantation (HSCT), by modulating T-cells with thioredoxin, a powerful, naturally occurring antioxidant molecule.
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