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Carvykti does a huge Bob Beamon jump and moves from 4th-line to 2nd-line CAR-T therapy for relapsed and refractory multiple myeloma

By claireoliverharwood

The recent FDA-mandated box warning for all 6 approved CAR-T therapies on potential secondary malignancies gave a massive fright to […]

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Liquid Biopsy Response Evaluation Criteria in Solid Tumors (LB-RECIST)

By claireoliverharwood

Current evaluation of treatment response in solid tumors depends on dynamic changes in tumor diameters as measured by imaging. However, […]

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Prognostic significance of circulating tumor cells and tumor related transcripts in small cell lung cancer: A step further to clinical implementation

By claireoliverharwood

Small-cell lung cancer (SCLC) is a fatal disease with limited treatment options. Circulating tumor cells (CTCs) in liquid biopsy samples […]

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Laboratory practice is central to earlier myeloma diagnosis: Utilizing a primary care diagnostic tool and laboratory guidelines integrated into haematology services

By claireoliverharwood

Treatment advances have greatly improved survival, but myeloma is among the worst of all cancers for delayed diagnosis, causing serious […]

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Osimertinib (Tagrisso) strengthens its position as the backbone therapy for EGFR-mutated lung cancer

By claireoliverharwood

According to the press release by AstraZeneca on February 19th, the use of Tagrisso (osimertinib) after chemoradiotherapy (CRT) in patients […]

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Predictors of unsustained measurable residual disease negativity in patients with multiple myeloma.

By claireoliverharwood

The prognostic impact of achieving and in particular maintaining measurable residual disease (MRD) negativity in multiple myeloma is now established; […]

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Clinical and biomarker results from a phase II trial of combined cabozantinib and durvalumab in patients with chemotherapy-refractory colorectal cancer (CRC): CAMILLA CRC cohort

By claireoliverharwood

Colorectal cancer (CRC) is the 4th most common cause of new cancer diagnosis and the 2nd leading cause of cancer-related […]

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Circulating and Imaging Biomarkers of Radium-223 Response in Metastatic Castration-Resistant Prostate Cancer

By claireoliverharwood

Radium-223 improves overall survival (OS) and reduces skeletal events in patients with bone metastatic castration-resistant prostate cancer (CRPC), but relevant […]

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Long-Term Follow-Up of the Anthracyclines in Early Breast Cancer Trials (USOR 06-090, NSABP B-46-I/USOR 07132, and NSABP B-49 [NRG Oncology])

By claireoliverharwood

The primary joint efficacy analysis of the Anthracyclines in Early Breast Cancer (ABC) trials reported in 2017, failed to demonstrate […]

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Amtagvi – first cellular therapy approval for unresectable melanoma

By claireoliverharwood

For patients with advanced-stage, unresectable or metastatic melanoma who have relapsed on prior systemic therapy, including a PD-1 blocking antibody […]

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Recent Posts
  • Poor Concordance Between Cancer Antigen-125 and RECIST Assessment for Progression in Patients With Platinum-Sensitive Relapsed Ovarian Cancer on Maintenance Therapy With a Poly(ADP-ribose) Polymerase Inhibitor
  • Are DNA Repair Gene Alterations Associated With the Response to Platinum-Based Regimen and Immune Checkpoint Inhibitors in Patients With Solid Tumors?
  • Axicabtagene ciloleucel versus standard of care in second-line large B-cell lymphoma: outcomes by metabolic tumor volume
  • Daiichi Sankyo and AstraZeneca does a Batman & Robin act and fires off its second ADC shot of 2024 with another FDA BLA for Dato-DXd
  • Is it time for PET-guided therapy in follicular lymphoma?
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