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General Medicine

General Medicine

Blood cancers: New generation stem cell transplant significantly reduces complications for patients

By Richard Hindle

Promising results for the UM171 molecule in blood stem cell transplants for patients with acute blood cancers.

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Next-generation sequencing detects rare fusion genes in sarcoma tumours

By Richard Hindle

Fox Chase Cancer Center researchers have determined that RNA-based next generation sequencing picks up gene fusions in sarcoma tumours that traditional gene testing may not.

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New diagnostic method finds aggressive tumours

By Richard Hindle

A discussion of a new genomic method, named CUTseq, which can assess the amount and type of CNAs in many different parts of the same tumour, at a much lower cost than existing technologies.

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Repurposing heart drugs to target cancer cells

By Richard Hindle

A discussion of the potential to repurpose cardiac glycosides, currently used to treat cardiac arrythmias and atrial fibrillation, to treat cancer.

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Discovery may lead to precision-based strategy for triple negative breast cancer

By Richard Hindle

According to the paper now available online, TP53 is the most frequently mutated gene in triple negative breast cancer, meaning it is fuelling the growth of this aggressive form of breast cancer. However, the problem with trying to target mutated TP53, specifically, is that it is not a druggable target, because of its potential toxicity – or ability to kill – nearby healthy cells.

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Conversion of breast cancer cells into fat cells impedes the formation of metastases

By Richard Hindle

An innovative combination therapy can force malignant breast cancer cells to turn into fat cells. This can be used to prevent the formation of metastases in mice, as researchers at the University of Basel’s Department of Biomedicine recently reported

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Breast cancer risk-factors and benefits of early screening

By AnnaH

Although breast cancer is the most common type of female cancer throughout the Middle East, many women do not seek medical care promptly. Consequently, the region has increased rates of late incidences. Dr Marwan Elbagouray explains breast cancer risks and the benefits of early screening.

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Adjuvant endocrine therapy: A cornerstone of systemic therapy for hormone receptor-positive breast cancer

By AnnaH

Adjuvant endocrine therapy remains a cornerstone of systemic therapy for hormone receptor-positive breast cancer. Dr Joyce Habib explains how there has been shift in the choice and duration of adjuvant endocrine therapy in pre and postmenopausal patients.

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Recent Posts
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  • Daiichi Sankyo and AstraZeneca does a Batman & Robin act and fires off its second ADC shot of 2024 with another FDA BLA for Dato-DXd
  • Is it time for PET-guided therapy in follicular lymphoma?
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