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Author: claireoliverharwood

Author: claireoliverharwood

Current Status of Prostate-specific Membrane Antigen-targeted Alpha Radioligand Therapy in Prostate Cancer

By claireoliverharwood

Prostate cancer (PCa) is the most prevalent malignancy and leading cause of mortality in men. Despite the development of various […]

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Pfizer’s oncology strategy and vision sounds like an invitation for ”the ride of your life”!

By claireoliverharwood

There are times when we are grateful to be given just a wee snippet of what’s important in the minds […]

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NGS greatly helps in overall management of NSCLC

By claireoliverharwood

A recent real-world study observed that 24% of patients with advanced non–small cell lung cancer (aNSCLC) with actionable driver oncogenes […]

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Circulating Tumor Cells Prediction in Hormone Receptor Positive HER2-Negative Advanced Breast Cancer: A Retrospective Analysis of the MONARCH 2 Trial

By claireoliverharwood

The MONARCH 2 trial (NCT02107703) showed the efficacy of abemaciclib, a cyclin-dependent kinase 4 & 6 inhibitor (CDK4/6i), in combination […]

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Validation of metastasis-free survival as a surrogate endpoint for overall survival in localized prostate cancer in the era of docetaxel for castration-resistant prostate cancer

By claireoliverharwood

Prior work from the Intermediate Clinical Endpoints in Cancer of the Prostate (ICECaP) consortium (ICECaP-1) demonstrated that metastasis-free survival (MFS) […]

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US Food and Drug Administration Approval Summary: Elacestrant for Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative, ESR1-Mutated Advanced or Metastatic Breast Cancer

By claireoliverharwood

The US Food and Drug Administration (FDA) approved elacestrant for the treatment of postmenopausal women or adult men with estrogen […]

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Association between Homologous Recombination Repair Defect Status and Long-Term Prognosis of Early HER2-Low Breast Cancer: A Retrospective Cohort Study

By claireoliverharwood

As a newly identified subtype of HER2-negative tumors associated with a less favorable prognosis, it remains crucial to evaluate potential […]

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Olaparib in Patients With Pancreatic Cancer With BRCA1/2 Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study

By claireoliverharwood

Targeted Agent and Profiling Utilization Registry (TAPUR) is a phase II basket trial evaluating the antitumor activity of commercially available […]

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Mobocertinib: UK to withdraw in EGFR+ exon 20 lung cancers…let’s EXCLAIM the results…

By claireoliverharwood

Patients with lung cancer who have EGFR exon 20 mutations typically have a poor prognosis. Other than chemotherapy, no other […]

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Use of chemotherapy in patients with oesophageal, stomach, colon, rectal, liver, pancreatic, lung, and ovarian cancer: an International Cancer Benchmarking Partnership (ICBP) population-based study

By claireoliverharwood

There are few data on international variation in chemotherapy use, despite it being a key treatment type for some patients […]

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Recent Posts
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